A cow's genome has been sequenced for the first time which
could pave the way to a livestock revolution, say scientists.
Experts believe understanding the genetic blueprint of domestic
cows will have a major impact on livestock breeding and will
help farmers boost milk production and create healthier herds.
The cow genome also has important implications for human health
because cattle and humans have about 80 per cent of their genes
in common.
The multimillion-pound project took more than 300 scientists
from 25 countries six years to complete.
The team unraveled 22,000 genes that make up the genetic code
of a Hereford cow living on a research farm in Montana, U.S.
The cow's DNA was then compared with cattle from six other
breeds. This was used to analyse variations of almost 500 cows
from 19 different regions.
As in humans, the chromosomes of cows - packages of DNA that
include the genes - were found to contain large duplicated regions.
In humans, these 'segmental duplications' are associated with
a range of problems including neurological disorders and birth
defects.
But in cows they were often beneficial, affecting genes related
to immunity, metabolism, digestion, reproduction and milk production.
Some of the chromosomal rearrangements are thought to explain
the cow's unique ability to convert grass and other low-energy
food sources into high-octane muscle, fat and milk.
'Diversity'
Dr Shirley Ellis from the Institute for Animal Health in Newbury,
Berkshire, said: 'This important achievement provides a sound
basis upon which to base future studies into the genetic diversity
present in different cattle breeds and populations.
'It is crucial that we preserve this variation through appropriate
breeding programmes in order to maintain healthy cattle populations
both in the UK and worldwide that are best able to cope with
climate change and emerging diseases.'
Cows join the exclusive club of animals who have had their
genome sequences including humans, rodents and other primates.
Professor Douglas Kell, chief executive of the Biotechnology
and Biological Sciences Research Council, which funded many
of the UK scientists, said: 'There is a looming crisis in food
production on the horizon.
'The inexorable growth in the global population and changing
consumption patterns in the developing world mean that even
before you include climate change we have to find ways to produce
more food with fewer resources.
'We need to recognise that livestock play a key role in many
people's diets. Research such as the cattle genome project underpins
the delivery of sustainable and nutritious meat with the highest
possible standards of animal welfare.'
Genome sequencing of other livestock including sheep, pigs
and goats is expected to follow.