"The
milestone publication in this week's Science (magazine) of not one, but two,
draft genome sequences of rice brings the cereal crop of the world's poor
to center stage," wrote Ronald P. Cantrell, director general of the
International Rice Research Institute (IRRI), and Timonthy G. Reeves,
director general of the International Maize and Wheat Improvement Center (CIMMYT),
in a commentary appearing in Science, where the genome information was
published.
"We
believe that the genome sequencing of the world's two most important rice
subspecies will be the first sequencing projects to yield tangible results
for humankind from the standpoints of food security and combating
malnutrition," Dr Cantrell said. The draft sequence of the
indica rice subspecies was done by the Beijing Genomics Institute (BGI) in
China, and the japonica subspecies was further sequenced by a team from
the Swiss company Syngenta. Both groups published their results in Science
this week amid predictions of the enormous potential impact on rice
production.
What
is so special about rice production? Put simply, no other economic
activity feeds so many people,
supports so many families, is so crucial to the development of so many
nations, or has more impact on our environment. Rice production
feeds almost half the planet each day, provides most of the main income
for millions of poor rural households, helps ensure social stability in
some of the world's biggest nations, and covers 11 percent of the earth's
arable area.
However,
Dr. Cantrell stressed that just as important as the actual
scientific advances achieved was the
public sharing of information by both groups. "IRRI advocates broad
collaborations in rice research that embrace innovations by both the
public and private sectors, with emphasis on the need to provide the best
science to serve the poor," he said. "The public availability of
the rice sequences published in this issue [of Science] will boost this
commitment.
"The
continuing challenge for all scientists is to broaden the developing
world's access to information and
technology," Dr. Cantrell said. "We must provide not only
finished products but also the technologies that will enable a new
generation of researchers in developing countries to solve their food
production problems."
In
light of this, Syngenta's efforts to negotiate a regime for making its
rice data available have been
welcomed by researchers at publicly funded institutions - particularly at
IRRI, which this week marked its 42nd year of helping to ensure global
food security and alleviate poverty.
"It
is extremely important that Syngenta continue its efforts to provide
nonprofit organizations, academic
institutions and governments free access to data on the rice genome,"
said Per Pinstrup-Anderson, director general of the International Food
Policy Research Institute (IFPRI) and winner of the 2001 World Food Prize.
"We encourage Syngenta to make all relevant data freely accessible in
the public domain." IFPRI is a sister Future Harvest center of
IRRI, both of them publicly funded through the Consultative Group on
International Agriculture (CGIAR)
IRRI,
like many of the other publicly funded Future Harvest centers, relies
on the broad sharing of genetic
information and seed stocks to breed crop varieties that offer farmers
higher yields, greater resistance to pests and diseases, improved
tolerance for drought, submergence and problem soils, as well as good
eating quality, and ready marketability.
Dr.
Cantrell also stressed that despite the great significance of the
sequencing work by the BGI and
Syngenta, a complete understanding of the rice genome has still not been
reached. "These drafts will be combined with a complete rice genome
sequence being compiled by the public International Rice Genome Sequencing
Project (IRGSP) coordinated by the Japan Rice Genome Program." The
finely detailed IRGSP sequence, which will have an error rate of less than
0.01 percent, is expected to be published by the end of this year.
"The
highly accurate IRGSP sequence will serve as the gold standard for all
future investigations of genetic
variation in crops," Dr Cantrell said, adding that by decoding the
rice genome, scientists had shed light on the larger, but parallel,
genomes of other agriculturally significant cereals such as wheat and
maize.
"Knowing
the sequence of specific genes will allow us to tap into the
natural genetic variation of crop
species," wrote Hei Leung, a plant pathologist at IRRI, and Pamela
Ronald, from the Department of Plant Pathology at the University of
California, Davis, in another commentary in Science. "In rice, there
are over 100,000 accessions of traditional rice varieties and wild species
(together referred to as germplasm) collected from a broad range of
geo-climates and held in trust" in the International Rice
Genebank at IRRI.
"These
rice seeds serve as a pool of 'natural variants' with the advantage
that some of these variants
(alleles) have already been 'tested' through years of natural or
artificial selection under different environmental conditions,"
Drs. Leung and Ronald continued. "To date, this wealth of information
has remained largely untapped owing to the difficulty of identifying
agronomically important genes.... The convergence of the different
versions of the genome sequence by the end of 2002 will yield great
insight into the relation between sequence diversity and functional
diversity in a wide variety of germplasm, the foundation on which
agricultural productivity depends."
"Although
achieving food security will require a multitude of social and
economic solutions, the new
knowledge derived from genomics research will make an important
contribution," they added. "The challenge ahead for the plant
research community is to design efficient ways to tap into the wealth of
rice genome sequence information to address production constraints in an
environmentally sustainable manner."
IRRI
is the world's leading international rice research and training center.
Based in the Philippines and with
offices in 11 other countries, it is an autonomous, nonprofit institution
focused on improving the well-being of present and future generations of
rice farmers and consumers, particularly those with low incomes, while
preserving natural resources. IRRI is one of 16 Future Harvest centers
funded the Consultative Group on International Agricultural Research (CGIAR),
an association of public and private donor agencies.
For
more information, visit the websites of CGIAR (www.cgiar.org
<http://www.cgiar.org/>)
or Future Harvest (www.futureharvest.org
<http://www.futureharvest.org/>).
Future Harvest is a nonprofit organization
that builds awareness and supports
food and environmental research for a world with less poverty, a healthier
human family, well-nourished children, and a better environment. Future
Harvest supports research, promotes partnerships, and sponsors projects
that bring the results of agricultural research to rural communities,
farmers, and families in Africa, Latin America, and Asia.
#
# #
For
additional information, contact Duncan Macintosh, IRRI, DAPO Box 7777,
Metro Manila, Philippines; telephone
(63-2) 845-0563 or (63-2) 844-3351 to 53; fax: (63-2) 891-1291 or (63-2)
845-0606; email: d.macintosh@cgiar.org
<mailto:d.macintosh@cgiar.org>
Web (IRRI): <http://www.irri.org/>
; Web (Library):
<http://ricelib.irri.cgiar.org/>
Web
(Riceweb): http://www.riceweb.org
; Web (Riceworld):
http://www.riceworld.org
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Related pages:
The International
Rice Genome Sequencing Project